Larger waist circumference linked to a higher risk of inflammation

Research has found that central obesity is a determinant for measuring a person’s state of inflammation. The study, which appeared in the journal Nutrition Research, was led by researchers from the University of ConnecticutUniversity of Florida; and the University of California, Irvine in the U.S.

  • The authors sought to associate biological markers for metabolic syndrome with that of inflammation and macronutrient intake.
  • The study involved 89 women between the ages of 25 to 72, all of whom have been diagnosed with metabolic syndrome.
  • Authors believed that waist circumference can be closely associated with inflammation. This, in turn, can be linked to a person’s overall carbohydrate intake.
  • Based on results, women with insulin resistance have increased levels of plasma triglycerides and a larger waist circumference.
  • In addition, they also observed variances in plasma glucose levels in those with insulin resistance.
  • Inflammation markers such as interleukin 6, tumor necrosis factor-alpha, and high-sensitivity C-reactive protein also varied widely, with most recorded to be above normal.
  • Researchers noted that participants had a high intake of sugar, high glycemic index, and glycemic load. Conversely, dietary fiber was below the recommended intake.

The findings revealed that women with a higher waist circumference had similarly increased carbohydrate, added sugar, and glycemic load.

Learn about other factors that contribute to chronic inflammation at

Journal Reference:

Ackermann D, Jones J, Barona J, Calle MC, Kim JE, Lapia B, Volek JS, Mcintosh M, Kalynych C, Najm W, et al. WAIST CIRCUMFERENCE IS POSITIVELY CORRELATED WITH MARKERS OF INFLAMMATION AND NEGATIVELY WITH ADIPONECTIN IN WOMEN WITH METABOLIC SYNDROME. Nutrition Research. March 2011;31(3):197–204. DOI: 10.1016/j.nutres.2011.02.004

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